OCCHIO Digital Imaging Analyzers are uniquely suited for particle size, shape, and distribution analysis, in the range of 200 nm to 3.0 mm. Depending on the size of the particles to be analyzed, what form they are in, ie...liquid or solid, and the volume of the sample, different dispersion techniques are employed relative to the required throughput, to provide optimal conditions for image capture.
What is unique, compared to other methods, specifically laser diffraction, and sieve analysis, is the ability to detect particle shape.
When you have the ability to measure, and quantify, particle shape parameters, particle size takes on a whole new meaning.
The 500 NANO P Analyzer is specifically designed for static, non destructive analysis of low volumes (Down to 1 ml) of very fine powders. With a fully automated sample placement process, contamination from dispersion is eliminated.
2-SHAPE INFORMATION ALLOWS FOR BETTER CORRELATION TO EXISTING METHODS
MANY INDUSTRIES HAVE THEIR STANDARDS ROOTED IN SIEVE ANALYSIS. SO ALTHOUGH LASER AND DIGITAL IMAGING
PROVIDE FOR MORE COMPREHENSIVE ANALYSIS, THEY STILL NEED TO BE ABLE TO CORRELATE TO SIEVE RESULTS.
REASONS TO TAKE PARTICLE SHAPE IN TO CONSIDERATION
WHAT IS UNIQUE WHEN COMPARED TO LASER DIFFRACTION AND SIEVE ANALYSIS
1- PARTICLE SHAPE AFFECTS THE PERFORMANCE ATTRIBUTES OF THE FINISHED PRODUCT
Assumptions of sphericity and random orientation may be sources of error for regular polygons
(eg, cubes), plates, or fibers.
LEFT-OCCHIO USES THE CONCEPT OF THE MAXIMUM INSCRIBED VIRTUAL DISC, TO MEASURE THE WIDEST PART OF THE PARTICLE, WHICH WOULD INDICATE WHICH SIEVE APERTURE THE PARTICLE WOULD BE RETAINED BY.
LASER DIFFRACTION DOES NOT HAVE THIS CAPABILITY.
RIGHT-A PICTURE OF A COFFEE GRIND,SHOWS THE PROBLEM WITH USING SIEVE ANALYSIS TO MEASURE THE SIZE OF NON SPHERICAL PARTICLES
AFTER DECADES OF RESEARCH IN OPTICS AND LIGHT, OCCHIO DEVELOPED A SPECIAL MONOCHROMATIC BACK LIGHT TO PROVIDE SUPERIOR PARTICLE DEFINITION. COMPARED TO NORMAL WHITE LIGHT,. ALLOWING THE DETECTION OF PARTICLES BELOW 1 MICRON.
THE BLUE LIGHT SOURCE IS COLLIMATED, AND ACTS LIKE A CALIPER, MEASURING ALL FACETS OF EACH PARTICLE IN HIGH DEFINITION.
Each analysis can be defined as an SOP, so that frequent tests can be run by several operators, with no need for programming, and the same results everytime.
After running an analysis, the comprehensive analytical software package Callsito tm, creates detailed reports, and provides bimodal, as well as three dimensional graphs,
showing shape and size distribution by number, or percentage.
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BENEFITS OF VACUUM SAMPLE DISPERSION
Maintains the integrity of the powder.
The Vacuum Disperser gently dissociates agglomerates.
Good orientation of each individual particle with natural sedimentation on the sample glass.
Eliminate artifacts with perfectly cleaned sample glass.
HOW IT WORKS:
A SMALL DISPOSABLE SAMPLE CUP WITH A TEAR-ABLE MEMBRANE FLOOR,
IS PLACED ON TOP OF THE VACUUM DISPERSION MODULE. WHEN THE VACUUM IS ENGAGED, THE MEMBRANE TEARS, AND THE SAMPLE POPULATES THE GLASS SLIDE, DEPOSITING MILLIONS OF PARTICLES IN OPTIMAL PLACEMENT FOR ANLYSIS, IN JUST A FEW SECONDS.
OCCHIO CALLISTO tm PHARMA SOFTWARE
COMPLETE REPORT GENERATION CAPABILITIES
21 CFR Part 11 Compliant
Copyright 2012: QAQC Lab | Particle Measurement System | All rights reserved.
OCCHIO DIGITAL IMAGE ANALYZERS HAVE THE ABILITY TO DETECT AND QUANTIFY BOTH PARTICLE SIZE AND PARTICLE SHAPE, PAVING THE WAY FOR THE ADVANCED ANALYSIS OF PARTICLES IN BOTH LIQUID AND SOLID FORMS.
CORRELATIONS TO OTHER PARTICLE SIZE ANALYSIS METHODS, LIKE SIEVE ANALYSIS AND LASER DIFFRACTION, ARE SEAMLESSLY EMPLOYED. EVEN SHAPE PARAMETERS LIKE LENGTH, FLATNESS, AND ANGULARITY IN AGGREGATES, OR THE LENGTH OF STRINGY PARTICLES LIKE SHREDDED CHEESE, OR TOBACCO, ARE POSSIBLE.
ONCE A BASIC CORRELATION HAS BEEN ESTABLISHED, THE RESULTS ARE FINE TUNED WITH THE OCCHIO CORRELATION PROGRAM, ALLOWING FOR TURNKEY SOLUTIONS TO PARTICLE CHARACTERIZATION.
