500 NANO PARTICLE CHARACTERIZATION SYSTEM FOR SMALL PRECISE AMOUNTS OF FINE POWDERS TO 400 nm
SAMPLE TYPE: 
VERY FINE POWDERS                          
DRY 400 nm to 2 mm 

SAMPLE TRANSPORT METHOD:
SPECIAL NON DESTRUCTIVE VACUUM 
PUMP AND TEAR ABLE MEMBRANE DISPERSION 
EQUIPMENT FOR QUALITY CONTROL AND R&D 
NANO 500 POWDER ANALYZER 
BROCHURE AND DATA SHEET 500 NANO
Occhio Digital Imaging Analyzers are uniquely suited for particle size, shape, and distribution   
analysis, in the range of 200 nm to 3.0 mm. Depending on the size of the particles to be analyzed, 
what form they are in, ie...liquid or solid, and the volume of the sample, different dispersion  techniques are employed relative to the required throughput, to provide optimal conditions for image capture.
​​What is unique, compared to other methods, specifically laser diffraction, and sieve analysis, is the ability to detect particle shape, instead of making the practical, but false assumption, that all particles are spherical. 

When you have the ability to measure, and quantify, particle shape parameters, particle size takes on a whole new meaning. 
The 500 NANO Analyzer is specifically designed for static, non destructive analysis of low volumes (Down to 1 ml) of very fine powders. The sample is placed in a small cup with a tearable membrane floor.
​A special vacuum pump is then used to tear the membrane, and deposit millions of particles on a glass slide, in just a few seconds.
The integrity of the powder is maintained, while agglomerates are gently dissociated, providing good orientation, and natural sedimentation on the glass slide.
WHAT IS UNIQUE COMPARED TO OTHER DIGITAL IMAGING DEVICES
3- PARTICLE SHAPE ANALYSIS ALLOWS FOR NEW OPPORTUNITIES IN R&D, AND QUALITY CONTROL
2-SHAPE INFORMATION ALLOWS FOR BETTER CORRELATION TO EXISTING METHODS

MANY INDUSTRIES HAVE THEIR STANDARDS DEFINED BY SIEVE ANALYSIS. SO ALTHOUGH LASER AND DIGITAL IMAGING
PROVIDE FOR MORE COMPREHENSIVE ANALYSIS, MORE ACCURATE, THEY STILL NEED TO BE ABLE TO CORRELATE TO SIEVE RESULTS.
THREE REASONS TO TAKE PARTICLE SHAPE IN TO CONSIDERATION 
WHAT IS UNIQUE WHEN COMPARED TO LASER DIFFRACTION AND SIEVE ANALYSIS
1- PARTICLE SHAPE AFFECTS THE PERFORMANCE ATTRIBUTES OF THE FINISHED PRODUCT  

BESIDES AFFECTING POWDER FLOW AND MIXING PROPERTIES, PARTICLE SHAPE IS CRITICAL IN THE EVALUATION
OF MATERIALS LIKE ABRASIVES, WHERE THE THERE IS REDUCED PERFORMANCE AS THE PARTICLE IS CLOSER TO    BEING SPHERICAL.
NEWLY DEFINED SHAPE PARAMETERS INCLUDE ROUGHNESS, AND BLUNTNESS ANALYSIS IN ABRASIVES,
WHERE THE DEVIATION FROM SPHERICITY IS MEASURED, ALONG WITH THE SHAPE OF THE ASPERITIES. 
LEFT-OCCHIO USES THE CONCEPT OF THE MAXIMUM INSCRIBED VIRTUAL DISC, TO MEASURE THE WIDEST PART OF THE PARTICLE WIDTH, WHICH WOULD INDICATE WHICH SIEVE APERTURE THE PARTICLE WOULD BE RETAINED BY. 
LASER DIFFRACTION DOES NOT HAVE THIS CAPABILITY.

RIGHT-A PICTURE OF A COFFEE GRIND,SHOWS THE PROBLEM WITH USING SIEVE ANALYSIS TO MEASURE THE SIZE OF NON SPHERICAL PARTICLES
AFTER YEARS OF RESEARCH IN OPTICS AND LIGHT, OCCHIO DEVELOPED A SPECIAL MONOCHROMATIC BACK LIGHT TO PROVIDE SUPERIOR PARTICLE DEFINITION. COMPARED TO NORMAL WHITE LIGHT,. ALLOWING THE DETECTION OF PARTICLES BELOW 1 MICRON.

THE BLUE LIGHT SOURCE IS COLLIMATED, AND ACTS LIKE  A CALIPER, MEASURING ALL FACETS OF  EACH PARTICLE IN HIGH DEFINITION. 
Each analysis may be defined as an SOP, so that frequent tests can be run by several operators, with no need for programming, and the same results every time.

After running an analysis, the comprehensive analytical software package Callsito tm creates detailed reports, in a variety of useful chart formats, including bimodal, boxplot, scatter plot, and 3-D, showing shape and size distribution by number, and or percentage.
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INTERNATIONAL SALES SERVICE SUPPORT NETWORK
SPECIAL DISPERSION CUP ALLOWS FOR SAMPLES AS SMALL AS 1ml TO BE ANALYZED.
Copyright 2012: QAQC Lab | Particle Measurement System | All rights reserved.
866-244-1578 | support@occhio-usa.com
www.occhio-usa.com
OCCHIO 500 NANOP FOR PHARMA
SEE ALSO:
OCCHIO 500 NANO XY WET/DRY
DIGITAL IMAGING EQUIPMENT FOR PARTICLE CHARACTERIZATION IN LIQUIDS, POWDERS, AND SOLIDS
HOMECONTACT USPRODUCTS

OCCHIO DIGITAL IMAGE ANALYZERS HAVE THE ABILITY TO DETECT AND QUANTIFY BOTH PARTICLE SIZE AND PARTICLE SHAPE, PAVING THE WAY FOR THE ADVANCED ANALYSIS OF PARTICLES IN BOTH LIQUID AND SOLID FORMS.

CORRELATIONS TO OTHER PARTICLE SIZE ANALYSIS METHODS, LIKE SIEVE ANALYSIS AND LASER DIFFRACTION, ARE SEAMLESSLY EMPLOYED. EVEN SHAPE PARAMETERS LIKE LENGTH, FLATNESS, AND ANGULARITY IN AGGREGATES, OR THE LENGTH OF STRINGY PARTICLES LIKE SHREDDED CHEESE, OR TOBACCO, ARE POSSIBLE.

ONCE A BASIC CORRELATION HAS BEEN ESTABLISHED, THE RESULTS ARE FINE TUNED WITH THE OCCHIO CORRELATION PROGRAM, ALLOWING FOR TURNKEY SOLUTIONS TO PARTICLE CHARACTERIZATION.
500 NANO SERIES500 NANO500 NANO PHARMA500 NANO XYCOFFEEE-TRAKFLOWCELL SERIES
FC200 IPACFC200MFC200SCMPSLURRYFC200SHRMORPHO 3-DPHARMA SCANNER
SIEVECALZEPHYR SERIESZEPHYR ESRZEPHYR LDAZEPHYR LDA COFFEE-TRAK

DIGITAL IMAGE ANALYZERS
DOWNLOADS
DIGITAL  PARTICLE
CHARACTERIZATION THEORY
EFFECTS OF DIGITIZATION
ON PARTICLE CHARACTERIZATION
AVAILABLE SIZE AND 
SHAPE PARAMETERS
SAMPLE 
CHARACTERISTICS

DISPERSION METHODS DESIGNED TO MAINTAIN PARTICLE INTEGRITY
GRANULAR MATERIALS, 
POWDERS, LIQUIDS

DRY GRANULAR MATERIALS 
SIZE RANGE 500 µm – 10,000 µm
EXAMPLES TABLETS, SEEDS, BEADS
3 DIMENSIONAL ANALYSIS 
DISPERSION METHOD
FEEDING HOPPER & CONVEYOR BELT
DRY POWDERS & GRANULARS
THAT TRAVEL WELL IN FLIGHT
7 µm – 5,000 µm 
EXAMPLES SUGAR / COFFEE / SAND
DISPERSION METHOD 
VIBRATING HOPPER WITH
HORIZONTAL VACUUM DISPERSION
 (FASTER ANALYSIS TIME)
LIQUID ANALYSIS FLOWCELL ACCESSORY
PARTICLES SUSPENDED IN LIQUID 1 µm – 3 mm
DRY GRANULARS HEAVIER PARTICLES 
30 µm – 30,000 µm
GRAVEL, WOOD CHIPS, SAND
COFFEE BEANS & GRINDS
DISPERSION METHOD
VIBRATING HOPPER WITH
VERTICAL DISPERSION (VACUUM ASSIST FOR DUST REMMOVAL)
LIQUID ANALYSIS FLOWCELL ACCESSORY
PARTICLES SUSPENDED IN LIQUID
30 µm – 1,000 µm 
FINE POWDERS
DRY 0.2 µm – 2,000 µm 
PHARMACEUTICALS, CHEMICALS
STATIC ANALYSIS
DISPERSION METHOD
PATENTED VACUUM IMPLOSION
LIQUID ANALYSIS FLOWCELL ACCESSORY
PARTICLES SUSPENDED IN LIQUID
.8 µm – 300 µm
DEDICATED LIQUID ANALYSIS
PARTICLES SUSPENDED IN LIQUID

​PARTICLES SUSPENDED IN LIQUID
0.8 µm-800 µm
DISPERSION METHOD
MEMBRANE PUMP (FOR PARTICLES SUBJECT 
TO BREAKAGE) 
PERILSTATIC PUMP (>500 µm)
PARTICLES SUSPENDED IN LIQUID
0.2 µm / 0.4 µm -1,000 µm
PROTEIN AGGREGATES
DISPERSION METHOD
SYRINGE PUMP
PARTICLES SUSPENDED IN LIQUID
SLURRIES
0.2 µm- 500 µm
DISPERSION METHOD
SYRINGE PUMP
SPECIAL DEDICATED 
APPLICATIONS
LABORATORY TEST SIEVE CALIBRATOR
CALIBRATE TEST SIEVES IN HOUSE.
2 MINUTES PER SIEVE.FULL INSPECTION / COMPLIANCE REPORT
PARTICLES IN LIQUIDS IN SITU
ANALYZE FIBERS, TEXTURES, AND PARTICLES INSIDE CONTAINERS
CLICK IMAGE FOR  PRODUCT DEMONSTRATION